Across TCGA patient cohorts, TCEAL2 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEAL2-associated genes across cancer lineages are EGFR_pY1068, IGFBP2, and JNK2. Each is linked with TCEAL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEAL2-to-partner and partner-to-TCEAL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEAL2→partner) and Y-score (partner→TCEAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.321	-2.459	.008	.020	2	2
UCEC	IGFBP2 →	-1.112	-3.584	<.001	.002	3	1
UCEC	JNK2 →	+0.310	+2.459	.001	.020	3	1
UCEC	Ku80 →	+0.325	+2.472	.004	.011	3	1
UCEC	Notch1 →	+0.249	+2.335	<.001	.018	3	1
UCEC	p90 RSK →	+0.186	+3.009	.044	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

TCEAL2 survival (RNA) · tumor vs normal (RNA) · all TCEAL2 data types