TCEAL1

Across TCGA pan-cancer cohorts, TCEAL1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TCEAL1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where TCEAL1 RNA is repressed in tumor relative to normal tissue. In most cancer types TCEAL1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and BLCA are the cancer types where TCEAL1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TCEAL1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.756	<.001	10	view →
THCA	Male	IV	−0.956	<.001	9	view →
BLCA	Male	III,IV	−1.757	<.001	8	view →
LIHC	Male	II,III,IV	+1.385	<.001	8	view →
LUSC	Female	II,III,IV	−1.232	<.001	8	view →
LUAD	Female	II,III,IV	−0.768	<.001	7	view →
UCEC	All	All	−2.218	<.001	6	view →
CHOL	All	All	+1.707	<.001	5	view →
KIRP	Male	All	−0.727	<.001	4	view →
KIRC	Male	II,III,IV	−0.291	.012	3	view →
PRAD	All	All	−0.660	<.001	2	view →
STAD	All	All	−0.649	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TCEAL1–KICH

Open the KICH breakdown →