Across TCGA patient cohorts, TCEA3 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEA3-associated genes across cancer lineages are STAT3_pY705, mTOR_pS2448, and Notch1. Each is linked with TCEA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEA3-to-partner and partner-to-TCEA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEA3→partner) and Y-score (partner→TCEA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.391	-2.321	<.001	.006	3	2
UCEC	mTOR_pS2448 →	-0.131	-3.308	.033	.009	3	1
UCEC	Notch1 →	+0.206	+2.009	<.001	.017	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.373	-2.459	.044	.019	3	1
UCEC	p62 Lck ligand →	+0.321	+1.807	.016	.027	3	1
UCEC	PCNA →	+0.215	+1.807	.016	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

TCEA3 survival (RNA) · tumor vs normal (RNA) · all TCEA3 data types