TCEA2

Across TCGA patient cohorts, TCEA2 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEA2-associated genes across cancer lineages are CD8+ T-cells, GMP, and Neutrophils. Each is linked with TCEA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEA2-to-partner and partner-to-TCEA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by TCEA2-low versus TCEA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEA2→partner) and Y-score (partner→TCEA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.012	+2.037	.011	.023	3	2
SKCM	GMP →	+0.058	+2.806	.001	.040	3	1
SKCM	Neutrophils →	+0.026	+3.615	<.001	.014	3	1
UCEC	CD8+ Tcm →	+0.030	+2.128	<.001	.019	3	1
UCEC	MEP →	+0.034	+1.818	.002	.016	3	1
UCEC	Neurons →	-0.017	-1.959	.030	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CD8+ T-cells by TCEA2 expression — UCEC

Explore this box plot interactively →