TCEA2

Across TCGA cell cohorts, TCEA2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TCEA2-associated genes across cancer lineages are PF4V1, PTH, and TPD52L3. Each is linked with TCEA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEA2-to-partner and partner-to-TCEA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PF4V1 grouped by TCEA2-low versus TCEA2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEA2→partner) and Y-score (partner→TCEA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PF4V1 →	+0.325	+3.793	<.001	.007	3	1
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	TPD52L3 →	+0.044	+3.684	<.001	.006	3	1
LARGE_INTESTINE	REG1B →	+4.044	+4.196	<.001	.002	3	1
LARGE_INTESTINE	CD300H →	+0.044	+5.000	<.001	<.001	3	1
BLOOD_Leukemia	TEX50 →	+0.027	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PF4V1 by TCEA2 expression — LARGE_INTESTINE

Explore this box plot interactively →