Across TCGA pan-cancer cohorts, TCEA1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TCEA1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TCEA1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TCEA1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where TCEA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.380	1.000	.008	32	view →
LSCC	OS	Quartile	All	1.000	0.720	.007	19	view →
LUAD	OS	Median	II,III,IV	1.000	0.862	.004	13	view →
UCEC	DFS	Median	All	1.000	0.941	.038	2	view →
GBM	OS	Median	All	0.475	0.291	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: TCEA1 tumor-vs-normal RNA expression · all TCEA1 data types