Across TCGA patient cohorts, TCEA1 mutation is significantly associated with the RNA expression of many other genes, with 1,026 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEA1-associated genes across cancer lineages are MBD3L5, EI24, and DLAT. Each is linked with TCEA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEA1-to-partner and partner-to-TCEA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEA1→partner) and Y-score (partner→TCEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MBD3L5 →	+0.127	+6.569	<.001	.001	3	2
UCEC	EI24 →	+0.504	+3.807	.007	<.001	3	1
UCEC	DLAT →	+0.636	+3.354	.004	.005	3	1
UCEC	CCDC3 →	-0.986	-3.807	.002	<.001	3	1
UCEC	CENPU →	+0.691	+2.732	.009	.003	3	1
UCEC	FAM168B →	+0.677	+3.329	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,026 associations by consensus.

Exploration

TCEA1 survival (RNA) · tumor vs normal (RNA) · all TCEA1 data types