Across TCGA patient cohorts, TCEA1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEA1-associated genes across cancer lineages are FoxM1, FOXO3a_pS318_S321, and ACC1. Each is linked with TCEA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEA1-to-partner and partner-to-TCEA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEA1→partner) and Y-score (partner→TCEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.414	+2.331	.001	.019	3	1
UCEC	FOXO3a_pS318_S321 →	-0.172	-2.999	.006	.035	3	1
UCEC	ACC1 →	+0.505	+2.820	.005	.035	3	1
UCEC	HER3_pY1289 →	+0.091	+2.827	.035	.035	3	1
UCEC	Ku80 →	+0.391	+3.183	<.001	.009	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.608	-3.446	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

TCEA1 survival (RNA) · tumor vs normal (RNA) · all TCEA1 data types