Across TCGA patient cohorts, TCAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,882 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TCAF1-associated genes across cancer lineages are TCAF1P1, MAD2L1, and ESCO2. Each is linked with TCAF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TCAF1-to-partner and partner-to-TCAF1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCAF1→partner) and Y-score (partner→TCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCAF1P1 →	+0.672	+0.225	<.001	<.001	3	7
COAD	MAD2L1 →	+0.802	+0.206	<.001	<.001	3	4
COAD	ESCO2 →	+0.779	+0.213	.001	.003	3	4
GBM	PPIAP22 →	+0.558	+0.435	<.001	<.001	3	4
BRCA	CDK5 →	+0.392	+0.293	<.001	<.001	3	4
GBM	UBE2T →	+0.727	+0.358	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,882 associations by consensus.

Exploration

TCAF1 survival (RNA) · tumor vs normal (RNA) · all TCAF1 data types