Across TCGA patient cohorts, TCAF1 mutation is significantly associated with the RNA expression of many other genes, with 143 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TCAF1-associated genes across cancer lineages are LINC00395, RNU6-660P, and XAGE1A. Each is linked with TCAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCAF1-to-partner and partner-to-TCAF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCAF1→partner) and Y-score (partner→TCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC00395 →	+0.059	+5.111	<.001	.004	3	2
HNSC	RNU6-660P →	+0.270	+5.468	<.001	.002	3	2
HNSC	XAGE1A →	+0.120	+5.008	<.001	.004	3	2
HNSC	XAGE1B →	+0.137	+6.020	<.001	<.001	3	2
HNSC	NCOR1P4 →	+1.603	+5.310	<.001	.001	3	1
HNSC	NF1P9 →	+0.135	+4.716	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

Exploration

TCAF1 survival (RNA) · tumor vs normal (RNA) · all TCAF1 data types