Across TCGA cell cohorts, TCAF1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TCAF1-associated genes across cancer lineages are IL4, TGM7, and OR8B12. Each is linked with TCAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCAF1-to-partner and partner-to-TCAF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCAF1→partner) and Y-score (partner→TCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IL4 →	+0.249	+4.222	.005	.007	3	1
SOFT_TISSUE	TGM7 →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR8B12 →	+0.049	+4.369	<.001	.008	3	1
SOFT_TISSUE	KRTAP20-2 →	+0.091	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR8B8 →	+0.029	+4.369	<.001	.008	3	1
SOFT_TISSUE	C4orf51 →	+0.056	+4.417	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

TCAF1 survival (RNA) · tumor vs normal (RNA) · all TCAF1 data types