TC2N

Across TCGA patient cohorts, TC2N RNA expression is significantly associated with the protein abundance of many other proteins, with 13,033 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TC2N-associated proteins across cancer lineages are TC2N_S156, TC2N_S174, and ATP8B1. Each is linked with TC2N in more than 9 cancer types. Because this analysis shows association rather than direction, both TC2N-to-partner and partner-to-TC2N results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TC2N versus TC2N_S156 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TC2N→partner) and Y-score (partner→TC2N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TC2N_S156 →	+1.328	+1.261	<.001	<.001	3	10
LSCC	TC2N_S174 →	+1.140	+1.273	<.001	<.001	3	8
OV	ATP8B1 →	+0.691	+0.737	<.001	.002	3	6
LUAD	TC2N_S168 →	+1.424	+1.134	<.001	<.001	3	6
BRCA	TRIP11 →	+0.299	+1.295	<.001	<.001	3	6
LUAD	TC2N_S218 →	+1.116	+1.044	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,033 associations by consensus.

TC2N vs TC2N_S156 — BRCA

Explore this scatter interactively →