TC2N

Across TCGA cell cohorts, TC2N RNA expression is significantly associated with the go_rna of many other GO terms, with 4,609 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TC2N-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Bundle of His cell to Purkinje myocyte communication, and Positive regulation of establishment of T cell polarity. Each is linked with TC2N in more than 10 cancer types. Because this analysis shows association rather than direction, both TC2N-to-partner and partner-to-TC2N results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytotoxic T cell degranulation grouped by TC2N-low versus TC2N-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TC2N→partner) and Y-score (partner→TC2N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytotoxic T cell degranulation →	+0.363	+3.250	<.001	<.001	3	11
PANCREAS	Bundle of His cell to Purkinje myocyte communication →	+0.274	+2.537	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of establishment of T cell polarity →	-0.244	-2.749	.001	<.001	3	10
BREAST	Positive regulation of collagen biosynthetic process →	-0.121	-2.296	.001	<.001	3	10
STOMACH	Establishment of apical/basal cell polarity →	-0.199	-2.194	<.001	.005	3	10
STOMACH	AV node cell to bundle of His cell communication by electrical coupling →	-1.123	-2.295	<.001	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,609 associations by consensus.

Cytotoxic T cell degranulation by TC2N expression — STOMACH

Explore this box plot interactively →