TBXAS1

Across TCGA pan-cancer cohorts, TBXAS1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TBXAS1 data layer compared with 22 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TBXAS1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBXAS1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where TBXAS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.919	1.000	.041	24	view →
LSCC	DFS	Median	II,III,IV	0.565	0.845	.024	5	view →
CCRCC	DFS	Quartile	III,IV	0.233	0.915	.017	4	view →
UCEC	DFS	Quartile	All	0.716	0.965	.017	4	view →
PDAC	OS	Median	II,III,IV	0.492	0.296	.031	3	view →
HNSC	DFS	Median	II,III,IV	0.895	0.976	.028	2	view →
LUAD	OS	Median	III,IV	0.750	0.998	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TBXAS1–COAD (DFS)

Open the COAD breakdown →