TBXAS1

Across TCGA cell cohorts, TBXAS1 mutation is significantly associated with the RNA expression of many other genes, with 998 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBXAS1-associated genes across cancer lineages are AVP, OXT, and BANF2. Each is linked with TBXAS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBXAS1-to-partner and partner-to-TBXAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by TBXAS1-low versus TBXAS1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBXAS1→partner) and Y-score (partner→TBXAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.039	+5.794	<.001	<.001	3	1
BLOOD_Lymphoma	OXT →	+0.046	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	BANF2 →	+0.071	+4.643	<.001	.005	3	1
LUNG_NSCLC_LUAD	DPPA5 →	+0.066	+4.544	<.001	.003	3	1
LARGE_INTESTINE	DEPDC5 →	+0.657	+3.321	<.001	.003	3	1
LARGE_INTESTINE	CBY1 →	+0.555	+3.160	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 998 associations by consensus.

AVP by TBXAS1 expression — BLOOD_Lymphoma

Explore this box plot interactively →