TBX3

Across TCGA patient cohorts, TBX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,488 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBX3-associated proteins across cancer lineages are TBX3_S456, TBX3_S707, and TBX3_S438. Each is linked with TBX3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TBX3-to-partner and partner-to-TBX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX3 versus TBX3_S456 in BRCA, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX3→partner) and Y-score (partner→TBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBX3_S456 →	+1.459	+2.092	<.001	<.001	3	9
BRCA	TBX3_S707 →	+1.093	+2.334	<.001	<.001	3	8
HNSC	TBX3_S438 →	+1.554	+1.618	<.001	<.001	3	7
GBM	DTX3 →	+0.650	+0.533	.002	.002	3	6
CCRCC	LAMA2 →	+0.843	+0.811	<.001	<.001	3	6
UCEC	TBX3_S375 →	+1.185	+1.667	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,488 associations by consensus.

TBX3 vs TBX3_S456 — BRCA

Explore this scatter interactively →