TBX3

Across TCGA patient cohorts, TBX3 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,379 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBX3-associated proteins across cancer lineages are TBX3_S707, MTCL1_S1514, and PBX1. Each is linked with TBX3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBX3-to-partner and partner-to-TBX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX3 versus TBX3_S707 in BRCA, with a Pearson correlation of 0.89.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX3→partner) and Y-score (partner→TBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBX3_S707 →	+1.257	+0.982	<.001	<.001	3	4
BRCA	MTCL1_S1514 →	+0.640	+0.602	<.001	<.001	3	3
UCEC	PBX1 →	+0.610	+0.519	<.001	<.001	3	3
UCEC	DTX3 →	+0.403	+0.524	<.001	<.001	3	3
BRCA	TBX3_S375 →	+1.515	+0.963	<.001	<.001	3	3
LSCC	STAT1 →	-0.631	-0.460	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,379 associations by consensus.

TBX3 vs TBX3_S707 — BRCA

Explore this scatter interactively →