TBX18

Across TCGA patient cohorts, TBX18 protein abundance is significantly associated with the RNA expression of many other genes, with 152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBX18-associated genes across cancer lineages are VTI1B, ALDOC, and TRIM38. Each is linked with TBX18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBX18-to-partner and partner-to-TBX18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX18 versus VTI1B in UCEC, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX18→partner) and Y-score (partner→TBX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VTI1B →	-0.312	-0.820	.007	.009	3	1
UCEC	ALDOC →	+2.152	+0.869	.008	.003	3	1
UCEC	TRIM38 →	+0.333	+0.678	.004	.008	3	1
UCEC	DAP →	+0.469	+0.731	.009	.003	3	1
UCEC	APBB3 →	+0.757	+0.980	.004	.001	3	1
UCEC	GRK7 →	+0.130	+0.882	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 152 associations by consensus.

TBX18 vs VTI1B — UCEC

Explore this scatter interactively →