TBX10

Across TCGA cell cohorts, TBX10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,601 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TBX10-associated GO terms across cancer lineages are Response to aldosterone, Bone marrow development, and Lactone catabolic process. Each is linked with TBX10 in more than 4 cancer types. Because this analysis shows association rather than direction, both TBX10-to-partner and partner-to-TBX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to aldosterone grouped by TBX10-low versus TBX10-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX10→partner) and Y-score (partner→TBX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Response to aldosterone →	+0.181	+0.398	<.001	.007	3	4
LUNG_SCLC	Bone marrow development →	+0.169	+0.667	.002	.009	3	4
BLOOD_Lymphoma	Lactone catabolic process →	-0.829	-0.514	<.001	<.001	3	4
BLOOD_Leukemia	Detoxification of copper ion →	-0.200	-0.157	.001	.005	3	4
BLOOD_Leukemia	Stress response to copper ion →	-0.200	-0.157	.001	.005	3	4
BLOOD_Leukemia	Protein localization to chromosome →	+0.075	+0.234	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,601 associations by consensus.

Response to aldosterone by TBX10 expression — BLOOD_Myeloma

Explore this box plot interactively →