Across TCGA cell cohorts, TBX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,549 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TBX1-associated GO terms across cancer lineages are Tongue morphogenesis, Soft palate development, and tRNA transcription. Each is linked with TBX1 in more than 14 cancer types. Because this analysis shows association rather than direction, both TBX1-to-partner and partner-to-TBX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX1→partner) and Y-score (partner→TBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Tongue morphogenesis →	-0.249	-1.326	<.001	.005	3	15
SOFT_TISSUE	Soft palate development →	+1.282	+2.051	<.001	<.001	3	14
BONE	tRNA transcription →	+0.119	+2.503	.006	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of skeletal muscle fiber differentiation →	+1.801	+2.671	<.001	.003	3	10
LUNG_NSCLC_LUSC	Positive regulation of skeletal muscle fiber differentiation →	+1.801	+2.671	<.001	.003	3	10
BONE	Base-excision repair, gap-filling →	+0.115	+2.510	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,549 associations by consensus.

Exploration

TBX1 survival (RNA) · tumor vs normal (RNA) · all TBX1 data types