TBRG1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TBRG1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TBRG1-associated genes across cancer lineages are DAZ4, TSHB, and OR6C68. Each is linked with TBRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBRG1-to-partner and partner-to-TBRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ4 grouped by TBRG1-low versus TBRG1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBRG1→partner) and Y-score (partner→TBRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEDAZ4 →+0.326+4.977<.001.00731
SKINTSHB →+0.219+6.022<.001.00131
SKINOR6C68 →+0.046+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DAZ4 by TBRG1 expression — LARGE_INTESTINE

Box plot of DAZ4 in TBRG1-low vs TBRG1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration