TBR1

Across TCGA cell cohorts, TBR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,179 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TBR1-associated GO terms across cancer lineages are Microtubule polymerization or depolymerization, Establishment of mitotic spindle localization, and Protein deneddylation. Each is linked with TBR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TBR1-to-partner and partner-to-TBR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization or depolymerization grouped by TBR1-low versus TBR1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBR1→partner) and Y-score (partner→TBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Microtubule polymerization or depolymerization →	+0.064	+0.026	.009	.009	3	7
PANCREAS	Establishment of mitotic spindle localization →	+0.078	+0.026	.002	.003	3	6
SKIN	Protein deneddylation →	+0.087	+0.043	.002	.007	3	6
OVARY	Transcription initiation at RNA polymerase III promoter →	+0.057	+0.035	<.001	.005	3	5
LIVER	Subtelomeric heterochromatin formation →	+0.101	+0.038	<.001	<.001	3	5
PANCREAS	Regulation of DNA-templated transcription elongation →	+0.042	+0.027	.007	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,179 associations by consensus.

Microtubule polymerization or depolymerization by TBR1 expression — PANCREAS

Explore this box plot interactively →