TBPL2

Across TCGA patient cohorts, TBPL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,950 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TBPL2-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, RNA 3'-end processing, and mRNA 3'-end processing. Each is linked with TBPL2 in more than 20 cancer types. Because this analysis shows association rather than direction, both TBPL2-to-partner and partner-to-TBPL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by TBPL2-low versus TBPL2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBPL2→partner) and Y-score (partner→TBPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.061	+0.156	<.001	<.001	3	21
STAD	RNA 3'-end processing →	+0.066	+0.169	<.001	<.001	3	20
STAD	mRNA 3'-end processing →	+0.067	+0.151	<.001	<.001	3	20
STAD	DNA-templated transcription elongation →	+0.071	+0.155	<.001	<.001	3	20
STAD	tRNA modification →	+0.057	+0.142	<.001	<.001	3	20
STAD	tRNA processing →	+0.061	+0.153	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,950 associations by consensus.

Positive regulation of DNA metabolic process by TBPL2 expression — STAD

Explore this box plot interactively →