TBPL1

Across TCGA patient cohorts, TBPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,820 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBPL1-associated genes across cancer lineages are MIB1, MED23, and HSF2. Each is linked with TBPL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBPL1-to-partner and partner-to-TBPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBPL1 versus MIB1 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBPL1→partner) and Y-score (partner→TBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MIB1 →	+0.455	+0.229	<.001	<.001	3	3
LSCC	MED23 →	+0.429	+0.320	<.001	<.001	3	3
GBM	HSF2 →	+0.653	+0.510	<.001	<.001	3	3
CCRCC	MIR133A1HG →	+0.581	+0.857	<.001	<.001	3	3
LSCC	THOC1 →	+0.468	+0.258	<.001	<.001	3	3
BRCA	TPSAB1 →	-1.045	-0.377	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,820 associations by consensus.

TBPL1 vs MIB1 — LSCC

Explore this scatter interactively →