TBPL1

Across TCGA cell cohorts, TBPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,369 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBPL1-associated GO terms across cancer lineages are Ribosomal small subunit export from nucleus, Negative regulation of ubiquitin protein ligase activity, and Protein-DNA complex assembly. Each is linked with TBPL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TBPL1-to-partner and partner-to-TBPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal small subunit export from nucleus grouped by TBPL1-low versus TBPL1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBPL1→partner) and Y-score (partner→TBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Ribosomal small subunit export from nucleus →	+0.123	+0.839	<.001	<.001	3	14
LUNG_SCLC	Negative regulation of ubiquitin protein ligase activity →	+0.249	+1.221	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein-DNA complex assembly →	+0.060	+0.653	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Transcription preinitiation complex assembly →	+0.065	+0.696	.001	.001	3	13
BLOOD_Lymphoma	Hair follicle placode formation →	+0.078	+0.718	.009	.005	3	12
LIVER	DNA replication-dependent chromatin assembly →	+0.122	+1.101	.002	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,369 associations by consensus.

Ribosomal small subunit export from nucleus by TBPL1 expression — SKIN

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