Across TCGA patient cohorts, TBL3 protein abundance is significantly associated with the RNA expression of many other genes, with 20,629 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBL3-associated genes across cancer lineages are HROB, CDCA8, and ABCA6. Each is linked with TBL3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TBL3-to-partner and partner-to-TBL3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL3→partner) and Y-score (partner→TBL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HROB →	+0.889	+0.227	<.001	<.001	3	9
UCEC	CDCA8 →	+1.276	+0.277	<.001	<.001	3	9
BRCA	ABCA6 →	-0.820	-0.294	<.001	<.001	3	9
LSCC	EME1 →	+0.875	+0.347	<.001	<.001	3	9
GBM	CHAF1B →	+0.705	+0.204	<.001	.003	3	9
HNSC	TEDC2 →	+0.984	+0.216	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,629 associations by consensus.

Exploration

TBL3 survival (RNA) · tumor vs normal (RNA) · all TBL3 data types