Across TCGA patient cohorts, TBL3 mutation is significantly associated with the RNA expression of many other genes, with 2,200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBL3-associated genes across cancer lineages are RN7SL55P, GAGE12H, and LINC00433. Each is linked with TBL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBL3-to-partner and partner-to-TBL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL3→partner) and Y-score (partner→TBL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SL55P →	+0.209	+5.149	<.001	.007	3	3
STAD	GAGE12H →	+0.660	+3.880	.001	.003	3	3
GBM	LINC00433 →	+0.094	+5.584	<.001	.003	3	2
CESC	SNORA74C-2 →	+0.191	+3.760	.001	.007	3	2
SKCM	UBAP1L →	+0.626	+2.768	.005	<.001	3	2
LIHC	SRP68P3 →	+0.144	+5.544	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,200 associations by consensus.

Exploration

TBL3 survival (RNA) · tumor vs normal (RNA) · all TBL3 data types