TBL2

Across TCGA cell cohorts, TBL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,544 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TBL2-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and Pre-mRNA catabolic process. Each is linked with TBL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TBL2-to-partner and partner-to-TBL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamic acid carboxylation grouped by TBL2-low versus TBL2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL2→partner) and Y-score (partner→TBL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Peptidyl-glutamic acid carboxylation →	+0.114	+0.764	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Protein carboxylation →	+0.114	+0.764	<.001	<.001	3	12
SKIN	Pre-mRNA catabolic process →	+0.165	+0.840	<.001	<.001	3	11
SKIN	Positive regulation of isotype switching to IgG isotypes →	+0.131	+0.965	<.001	<.001	3	9
KIDNEY	Receptor recycling →	+0.057	+0.742	.005	.001	2	10
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.044	+0.780	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,544 associations by consensus.

Peptidyl-glutamic acid carboxylation by TBL2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →