TBL1Y

Across TCGA cell cohorts, TBL1Y RNA expression is significantly associated with the mutation status of many other genes, with 192 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible TBL1Y-associated genes across cancer lineages are RUNX1T1, CD101, and MUC5B. Each is linked with TBL1Y in more than 2 cancer types. Because this analysis shows association rather than direction, both TBL1Y-to-partner and partner-to-TBL1Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RUNX1T1 grouped by TBL1Y-low versus TBL1Y-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL1Y→partner) and Y-score (partner→TBL1Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	RUNX1T1 →	+4.614	+0.005	.004	<.001	3	3
LUNG_NSCLC_LUSC	CD101 →	+4.643	+0.053	.008	<.001	3	3
SOFT_TISSUE	MUC5B →	+1.984	+0.182	.009	<.001	3	2
PANCREAS	ALDH1L2 →	+5.614	+0.006	.002	<.001	3	2
PANCREAS	JCAD →	+4.029	+0.004	.007	<.001	3	2
PANCREAS	TMEM132C →	+5.614	+0.006	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

RUNX1T1 by TBL1Y expression — PANCREAS

Explore this box plot interactively →