Across TCGA patient cohorts, TBKBP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 4,097 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBKBP1-associated proteins across cancer lineages are RBCK1_S272, KLK6, and TMEM30B. Each is linked with TBKBP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBKBP1-to-partner and partner-to-TBKBP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBKBP1→partner) and Y-score (partner→TBKBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBCK1_S272 →	-0.543	-0.479	<.001	.001	3	2
CCRCC	KLK6 →	+1.250	+0.490	.001	.001	3	2
HNSC	TMEM30B →	+1.397	+0.957	<.001	.002	3	2
CCRCC	ATAD2_S342 →	-1.484	-0.506	<.001	.001	3	2
LSCC	ECE1_T25 →	+1.011	+1.330	.001	<.001	3	2
UCEC	OSBP_S351 →	-1.438	-0.440	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,097 associations by consensus.

Exploration

TBKBP1 survival (RNA) · tumor vs normal (RNA) · all TBKBP1 data types