Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, TBK1 mutation is significantly associated with the RNA expression of many other genes, with 5,504 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible TBK1-associated genes across cancer lineages are DNAJB8-AS1, RNU6-902P, and SSRP1. Each is linked with TBK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBK1-to-partner and partner-to-TBK1 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (TBK1→partner) and Y-score (partner→TBK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.