TBCEL

Across TCGA patient cohorts, TBCEL mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBCEL-associated genes across cancer lineages are c-Met_pY1235, Caveolin-1, and p27_pT198. Each is linked with TBCEL in more than 1 cancer types. Because this analysis shows association rather than direction, both TBCEL-to-partner and partner-to-TBCEL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, c-Met_pY1235 grouped by TBCEL-low versus TBCEL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCEL→partner) and Y-score (partner→TBCEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	c-Met_pY1235 →	+0.077	+3.009	.039	.019	3	1
UCEC	Caveolin-1 →	-0.748	-2.321	.040	.035	2	1
UCEC	p27_pT198 →	+0.119	+2.321	.026	.035	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

c-Met_pY1235 by TBCEL expression — UCEC

Explore this box plot interactively →