TBCEL

Across TCGA cell cohorts, TBCEL mutation is significantly associated with the mutation status of many other genes, with 805 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBCEL-associated genes across cancer lineages are CHST9, KBTBD3, and GRIA2. Each is linked with TBCEL in more than 2 cancer types. Because this analysis shows association rather than direction, both TBCEL-to-partner and partner-to-TBCEL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHST9 grouped by TBCEL-low versus TBCEL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCEL→partner) and Y-score (partner→TBCEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CHST9 →	+3.350	+4.584	.003	.003	1	3
SKIN	KBTBD3 →	+5.392	+4.824	.004	.004	1	3
SOFT_TISSUE	GRIA2 →	+5.066	+4.502	.007	.007	1	3
SKIN	FEZ1 →	+4.392	+4.392	.009	.009	1	3
SKIN	EPHA3 →	+2.977	+4.392	.005	.005	1	2
SKIN	NCBP3 →	+4.392	+5.357	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 805 associations by consensus.

CHST9 by TBCEL expression — LARGE_INTESTINE

Explore this box plot interactively →