TBCE

Across TCGA cell cohorts, TBCE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,358 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBCE-associated GO terms across cancer lineages are Tubulin complex assembly, Nuclear pore organization, and Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Each is linked with TBCE in more than 15 cancer types. Because this analysis shows association rather than direction, both TBCE-to-partner and partner-to-TBCE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tubulin complex assembly grouped by TBCE-low versus TBCE-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCE→partner) and Y-score (partner→TBCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Tubulin complex assembly →	+0.115	+0.843	<.001	<.001	3	16
SOFT_TISSUE	Nuclear pore organization →	+0.181	+0.719	<.001	<.001	3	15
STOMACH	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.129	+0.690	<.001	.002	3	15
SOFT_TISSUE	Nuclear pore complex assembly →	+0.160	+0.701	<.001	<.001	3	13
STOMACH	Establishment of protein localization to endoplasmic reticulum membrane →	+0.093	+0.595	<.001	<.001	3	12
SOFT_TISSUE	Regulation of formation of translation preinitiation complex →	+0.082	+0.566	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,358 associations by consensus.

Tubulin complex assembly by TBCE expression — BREAST

Explore this box plot interactively →