TBCD

Across TCGA pan-cancer cohorts, TBCD mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TBCD data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TBCD mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TBCD expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where TBCD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.553	1.000	.002	15	view →
CCRCC	DFS	Tertile	All	1.000	0.887	.025	11	view →
HNSC	OS	Tertile	All	0.785	0.920	.030	2	view →
PDAC	OS	Tertile	All	0.389	0.576	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TBCD–LUAD (OS)

Open the LUAD breakdown →