tubulin folding cofactor A pseudogene 1Genealiases: []
Q-omics provides the consensus-scored TBCAP1 profile across patient tissues and cancer cell-line models. TBCAP1 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, TBCAP1 is differentially expressed in 11, with the highest sampling consensus in KIRC. Additionally, TBCAP1 RNA expression shows 17,931 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KICH, KIRC, and ACC as cancer lineages where TBCAP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TBCAP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TBCAP1 survival associations across molecular data types. TBCAP1 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TBCAP1 RNA expression–survival associations across cancer types. High TBCAP1 expression shows unfavorable associations in KICH, HNSC, UCEC, OV, UVM and LIHC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KICH as the clearest survival context for TBCAP1 RNA expression.
This table summarizes TBCAP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TBCAP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TBCAP1 shows lower tumor expression in KICH and higher tumor expression in KIRC, LIHC, BRCA, CHOL and HNSC. The KIRC box plot shows higher TBCAP1 RNA expression in tumor versus normal tissue (log2 FC = +0.527, t-test p < 0.001).
This table shows molecular features associated with TBCAP1 in patient tissues and cancer cell lines. In patient samples, TBCAP1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
