TBCA

Across TCGA cell cohorts, TBCA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,567 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TBCA-associated GO terms across cancer lineages are Dihydrofolate metabolic process, Regulation of centriole elongation, and Cell-cell junction organization. Each is linked with TBCA in more than 13 cancer types. Because this analysis shows association rather than direction, both TBCA-to-partner and partner-to-TBCA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by TBCA-low versus TBCA-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCA→partner) and Y-score (partner→TBCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Dihydrofolate metabolic process →	+0.201	+0.610	.003	.009	3	14
OVARY	Regulation of centriole elongation →	+0.069	+0.541	.004	.004	3	9
BREAST	Cell-cell junction organization →	-0.056	-0.508	<.001	.001	3	8
BLOOD_Myeloma	Positive regulation of ligase activity →	+0.100	+0.823	.002	.002	3	8
PANCREAS	Regulation of nucleocytoplasmic transport →	-0.074	-0.603	.001	.003	3	8
LARGE_INTESTINE	DAMP biosynthetic process →	+0.101	+0.469	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,567 associations by consensus.

Dihydrofolate metabolic process by TBCA expression — LIVER

Explore this box plot interactively →