Across TCGA patient cohorts, TBC1D9B mutation is significantly associated with the total protein of many other genes, with 71 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D9B-associated genes across cancer lineages are Caspase-7-cleavedD198, p21, and ATM. Each is linked with TBC1D9B in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D9B-to-partner and partner-to-TBC1D9B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D9B→partner) and Y-score (partner→TBC1D9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.094	+3.807	<.001	<.001	3	3
UCEC	p21 →	+0.159	+2.169	.005	.003	3	3
COAD	ATM →	-0.612	-2.321	<.001	.004	3	3
COAD	p38-MAPK →	+0.147	+2.008	.017	.005	3	3
STAD	TIGAR →	+0.419	+3.169	.023	.018	3	2
UCEC	14-3-3_beta →	-0.079	-1.880	.008	.014	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

Exploration

TBC1D9B survival (RNA) · tumor vs normal (RNA) · all TBC1D9B data types