Across TCGA cell cohorts, TBC1D9B mutation is significantly associated with the RNA expression of many other genes, with 908 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBC1D9B-associated genes across cancer lineages are TNRC6B, UBE2G1, and TTPA. Each is linked with TBC1D9B in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D9B-to-partner and partner-to-TBC1D9B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D9B→partner) and Y-score (partner→TBC1D9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNRC6B →	+0.760	+3.234	<.001	.004	3	2
LARGE_INTESTINE	UBE2G1 →	+0.556	+2.675	.003	.003	3	2
LARGE_INTESTINE	TTPA →	+0.724	+3.628	.008	<.001	3	2
LARGE_INTESTINE	SEC24B →	+0.513	+2.502	.009	.005	3	2
LARGE_INTESTINE	GAL3ST2 →	+1.632	+2.502	<.001	.005	3	2
LARGE_INTESTINE	BUB3 →	+0.415	+3.067	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 908 associations by consensus.

Exploration

TBC1D9B survival (RNA) · tumor vs normal (RNA) · all TBC1D9B data types