TBC1D9

Across TCGA patient cohorts, TBC1D9 mutation is significantly associated with the RNA expression of many other genes, with 3,549 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D9-associated genes across cancer lineages are GOT1, ATP1B2, and MYRF-AS1. Each is linked with TBC1D9 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D9-to-partner and partner-to-TBC1D9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOT1 grouped by TBC1D9-low versus TBC1D9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D9→partner) and Y-score (partner→TBC1D9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GOT1 →	+0.471	+2.738	<.001	.002	3	4
UCEC	ATP1B2 →	-0.738	-4.512	<.001	<.001	3	4
COAD	MYRF-AS1 →	+0.248	+3.547	.006	.002	3	4
SKCM	SLC22A17 →	-1.140	-1.968	.002	.003	3	3
STAD	PTMAP4 →	+1.791	+3.186	<.001	.009	3	3
COAD	TXNL1 →	+0.443	+2.861	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,549 associations by consensus.

GOT1 by TBC1D9 expression — SKCM

Explore this box plot interactively →