TBC1D5

Across TCGA patient cohorts, TBC1D5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,743 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TBC1D5-associated genes across cancer lineages are MARCHF1, OXNAD1, and CMC1. Each is linked with TBC1D5 in more than 5 cancer types. Because this analysis shows association rather than direction, both TBC1D5-to-partner and partner-to-TBC1D5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D5 versus MARCHF1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D5→partner) and Y-score (partner→TBC1D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MARCHF1 →	+0.647	+0.240	<.001	<.001	3	6
HNSC	OXNAD1 →	+0.590	+0.248	<.001	<.001	3	6
HNSC	CMC1 →	+0.496	+0.240	<.001	<.001	3	6
OV	METTL6 →	+0.456	+0.294	.001	<.001	3	6
BRCA	PNP →	-0.703	-0.233	<.001	<.001	3	5
HNSC	C21orf62-AS1 →	+0.403	+0.202	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,743 associations by consensus.

TBC1D5 vs MARCHF1 — HNSC

Explore this scatter interactively →