TBC1D5

Across TCGA patient cohorts, TBC1D5 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,253 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TBC1D5-associated proteins across cancer lineages are TBC1D5_S43, TBC1D5_S522, and TBC1D5_S541. Each is linked with TBC1D5 in more than 6 cancer types. Because this analysis shows association rather than direction, both TBC1D5-to-partner and partner-to-TBC1D5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D5 versus TBC1D5_S43 in OV, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D5→partner) and Y-score (partner→TBC1D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TBC1D5_S43 →	+0.821	+0.246	<.001	<.001	3	6
OV	TBC1D5_S522 →	+0.864	+0.193	<.001	.005	2	7
OV	TBC1D5_S541 →	+0.617	+0.180	.001	.001	3	6
OV	TBC1D5_S554 →	+0.536	+0.159	.001	.004	2	7
GBM	HNMT →	+0.468	+0.187	<.001	<.001	3	6
CCRCC	MKRN2 →	+0.248	+0.116	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,253 associations by consensus.

TBC1D5 vs TBC1D5_S43 — OV

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