TBC1D5

Across TCGA cell cohorts, TBC1D5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,914 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TBC1D5-associated GO terms across cancer lineages are Peptidyl-serine modification, Positive regulation of pinocytosis, and Regulation of smoothened signaling pathway. Each is linked with TBC1D5 in more than 13 cancer types. Because this analysis shows association rather than direction, both TBC1D5-to-partner and partner-to-TBC1D5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-serine modification grouped by TBC1D5-low versus TBC1D5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D5→partner) and Y-score (partner→TBC1D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Peptidyl-serine modification →	+0.067	+1.147	<.001	<.001	3	14
URINARY_TRACT	Positive regulation of pinocytosis →	+0.147	+1.212	<.001	<.001	3	14
OESOPHAGUS	Regulation of smoothened signaling pathway →	+0.043	+0.986	.006	.007	3	14
LIVER	Regulation of chromosome organization →	+0.067	+0.882	.002	.004	3	14
STOMACH	Negative regulation of hippo signaling →	+0.091	+1.115	.001	<.001	3	13
LIVER	Mitotic spindle assembly →	+0.109	+0.837	<.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,914 associations by consensus.

Peptidyl-serine modification by TBC1D5 expression — BREAST

Explore this box plot interactively →