TBC1D4

Across TCGA patient cohorts, TBC1D4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,403 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TBC1D4-associated genes across cancer lineages are TMTC4, MCF2L, and FARP1. Each is linked with TBC1D4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D4-to-partner and partner-to-TBC1D4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D4 versus TMTC4 in LSCC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D4→partner) and Y-score (partner→TBC1D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMTC4 →	+0.632	+0.384	<.001	<.001	3	4
GBM	MCF2L →	+0.795	+0.240	<.001	.002	3	4
COAD	FARP1 →	+0.736	+0.305	<.001	<.001	3	4
LSCC	RMND5A →	+0.631	+0.374	.001	.004	3	4
GBM	MCF2 →	+0.605	+0.231	.003	<.001	3	3
OV	SLC25A15 →	+0.455	+0.283	.002	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,403 associations by consensus.

TBC1D4 vs TMTC4 — LSCC

Explore this scatter interactively →