Across TCGA patient cohorts, TBC1D3P2 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D3P2-associated genes across cancer lineages are Notch1, EGFR_pY1068, and eIF4E. Each is linked with TBC1D3P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3P2-to-partner and partner-to-TBC1D3P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3P2→partner) and Y-score (partner→TBC1D3P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.181	+3.472	.001	.002	3	2
UCEC	EGFR_pY1068 →	-0.314	-3.169	.001	<.001	3	1
UCEC	eIF4E →	+0.175	+3.183	.034	.009	3	1
UCEC	ERK2 →	+0.252	+3.700	<.001	.001	3	1
UCEC	FOXO3a_pS318_S321 →	-0.131	-1.797	.007	.025	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.437	+1.817	.028	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

TBC1D3P2 survival (RNA) · tumor vs normal (RNA) · all TBC1D3P2 data types