TBC1D3J

Across TCGA pan-cancer cohorts, TBC1D3J RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated TBC1D3J data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher TBC1D3J RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D3J expression acts as an unfavorable survival marker, although some lineages such as STAD and CESC show a favorable association.

TGCT, COAD, and UVM are the cancer types where TBC1D3J RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	III,IV	0.010	1.000	<.001	72	view →
COAD	DFS	Tertile	II,III,IV	0.537	0.770	<.001	54	view →
UVM	OS	Tertile	All	0.305	0.796	.001	45	view →
KIRP	DFS	Tertile	All	0.763	0.891	.011	45	view →
STAD	OS	Tertile	IV	0.711	0.243	.012	35	view →
LGG	DFS	Tertile	All	0.696	0.838	.002	30	view →
MESO	OS	Tertile	II,III,IV	0.137	0.587	.004	27	view →
THYM	DFS	Tertile	All	0.551	0.823	.034	18	view →
CESC	OS	Tertile	IV	1.000	0.243	.044	18	view →
PRAD	DFS	Tertile	All	0.634	0.799	.003	18	view →
SKCM	DFS	Tertile	III,IV	0.466	0.655	.006	15	view →
BRCA	DFS	Tertile	II,III,IV	0.508	0.532	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

TBC1D3J–TGCT (DFS)

Open the TGCT breakdown →