TBC1D32

Across TCGA patient cohorts, TBC1D32 mutation is significantly associated with the RNA expression of many other genes, with 3,067 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D32-associated genes across cancer lineages are KIF18A, EXOSC9, and SMCO4. Each is linked with TBC1D32 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D32-to-partner and partner-to-TBC1D32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIF18A grouped by TBC1D32-low versus TBC1D32-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D32→partner) and Y-score (partner→TBC1D32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF18A →	+0.614	+1.868	<.001	<.001	3	3
UCEC	EXOSC9 →	+0.364	+1.658	.002	.001	3	3
UCEC	SMCO4 →	+0.734	+1.857	<.001	<.001	3	3
BLCA	HMGB1P7 →	+0.228	+4.004	<.001	.006	3	3
BRCA	MIR6505 →	+0.814	+4.030	<.001	.006	3	2
UCEC	FRG1HP →	+0.443	+1.669	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,067 associations by consensus.

KIF18A by TBC1D32 expression — UCEC

Explore this box plot interactively →