TBC1D32

Across TCGA cell cohorts, TBC1D32 mutation is significantly associated with the RNA expression of many other genes, with 622 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBC1D32-associated genes across cancer lineages are DPRX, LGI1, and VSX1. Each is linked with TBC1D32 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D32-to-partner and partner-to-TBC1D32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPRX grouped by TBC1D32-low versus TBC1D32-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D32→partner) and Y-score (partner→TBC1D32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DPRX →	+0.166	+5.060	<.001	.001	3	2
BLOOD_Leukemia	LGI1 →	+0.096	+4.539	<.001	.007	3	2
URINARY_TRACT	VSX1 →	+0.195	+3.523	.002	.009	3	1
URINARY_TRACT	POTEJ →	+0.032	+3.584	<.001	.009	3	1
STOMACH	ACER1 →	+0.067	+4.366	<.001	<.001	3	1
STOMACH	NTSR2 →	+0.200	+3.954	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 622 associations by consensus.

DPRX by TBC1D32 expression — BLOOD_Leukemia

Explore this box plot interactively →