TBC1D30

Across TCGA pan-cancer cohorts, TBC1D30 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TBC1D30 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TBC1D30 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TBC1D30 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, PDAC, and LSCC are the cancer types where TBC1D30 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.965	0.785	.020	8	view →
PDAC	OS	Median	IV	0.194	0.956	.038	6	view →
LSCC	DFS	Tertile	All	1.000	0.258	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TBC1D30–UCEC (DFS)

Open the UCEC breakdown →