TBC1D30

Across TCGA patient cohorts, TBC1D30 protein abundance is significantly associated with the RNA expression of many other genes, with 6,533 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TBC1D30-associated genes across cancer lineages are ANKLE1, SH3BP1, and GALNT7. Each is linked with TBC1D30 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D30-to-partner and partner-to-TBC1D30 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D30 versus ANKLE1 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D30→partner) and Y-score (partner→TBC1D30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANKLE1 →	-0.752	-0.417	<.001	.003	3	4
UCEC	SH3BP1 →	-0.548	-0.614	<.001	<.001	3	3
BRCA	GALNT7 →	+0.982	+0.668	.006	<.001	3	3
PDAC	CBL →	-0.400	-0.732	<.001	<.001	3	3
BRCA	ARFGEF3 →	+1.159	+0.682	<.001	<.001	3	3
UCEC	ELAPOR1 →	+2.160	+0.420	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,533 associations by consensus.

TBC1D30 vs ANKLE1 — UCEC

Explore this scatter interactively →